ACP Journal Club

(更新日 2005年11月1日)
 ACP Journal Clubの紹介(タイトル和訳)
  January/February 2004 Vol 140 Number 1 (内科専門医会誌 Vol.16 2004 May)
  (福岡大学医学部 第二内科 岡村圭祐/藤野正礼/谷川宏之/野田慶太/
朔啓二郎 )

Simvastatin reduced mortality and vascular events in diabetes mellitus.
Collins R, Armitage J, Parish S, et al. Lancet. 2003; 361: 2005-16


Acarbose reduced the risk for cardiovascular disease and hypertension in impaired glucose tolerance.
Chiasson JL, Josse RG, Gomis R, et al. JAMA. 2003; 290: 486-94


Review: low-dose diuretics are the best first-line antihypertensive therapy.
Psaty BM, Lumley T, Furberg CD, et al. JAMA. 2003; 289: 2534-44.


Review: lower-dose combination antihypertensive therapy is preferable to standard-dose single-drug therapy.
Law MR, Wald NJ, Morris JK, Jordan RE. BMJ. 2003; 326: 1427-34


Carvedilol was more effective than metoprolol tartrate for lowering mortality in chronic heart failure.
Poole-Wilson PA, Swedberg K, Cleland JG, et al. Lancet. 2003; 362: 7-13

慢性心不全の患者においてcarvedilolはmetoprolol tartrateよりも全死亡率や心血管疾患による死亡率を減少させるのに有効である.

Review: amiodarone is effective for converting atrial fibrillation to sinus rhythm.
Letelier LM, Udol K, Ena J, Weaver B, Guyatt GH. Arch Intern Med. 2003; 163: 777-85


Review: comprehensive occupational therapy interventions improve outcomes after stroke.
Steultjens EM, Dekker J, Bouter LM, et al. Stroke. 2003; 34: 676-87.


An intervention to treat depression and increase social support did not prolong event-free survival in coronary heart disease.
ENRICHD Investigators. JAMA 2003; 289: 3106-16


Ticlopidine was not better than aspirin for preventing recurrent stroke in African-Americans with noncardioembolic ischemic stroke.
Gorelick PB, Richardson D, Kelly, et al. JAMA. 2003; 289: 2947-57


Dalteparin reduced recurrent venous thromboembolism more than oral anticoagulation in patients with cancer.
Lee AY, Levine MN, Baker RI, et al. N Eng J Med. 2003; 349: 146-53


A scheduled second endoscopy 16 to 24 hours after initial endoscopic hemostatis reduced recurrent peptic ulcer bleeding.
Chiu PW, Lam CY, Lee SW, et al. Gut. 2003; 52: 1403-7


Review: Regular inhaled short-acting β2-agonists improve lung function in stable chronic obstructive pulmonary disease.
Ram FS, Sestini P. Thorax. 2003; 58: 580-4


Review: Omalizumab reduced asthma exacerbations and daily steroid use.
Walker S, Monteil M, Phelan K, Lasserson TJ, Walters EH. Cochrane Database Syst Rev. 2003; (3): CD003559


Inhaled corticosteroids were safely stepped down in chronic, stable asthma.
Hawkins G, Mcmahon AD, Twaddle S, et al. BMJ. 2003; 326: 1115-20


Anticholinergic drugs improve motor function and disability in parkinson disease.
Katzenschlager R, Sampaio C, Costa J, Lees A. cochrane database syst rev. 2003; (2): CD 003735


Intravenous N-acetylcysteine prevented contrast nephropathy.
Baker CS, Wragg A, Kumar S, et al. J Am Coll Cardiol. 2003; 41: 2114-8.


Therapeutic knee taping improved pain and disability in osteoarthritis of the knee.
Hinman RS, Crossley KM, McConnell, Bennell KL. BMJ. 2003; 327: 135-8.


Review: The cosyntropin-stimulation test has limited value for detecting and excluding adrenal insufficiency
Dorin RI, Qualls CR, Crapo LM.Ann Intern Med. 2003; 139; 194-204.

250-μgおよび1-μg cosyntropin刺激試験は同様の診断的特性を有する.cosyntropin試験は二次性副腎機能不全を検出するのに有用であるが,除外するのに有用ではないかもしれない.

Diabetes and other comorbid conditions were associated with a poor outcome in SARS.
Booth CM, Matukas LM, Tomlinson GA, et al. JAMA. 2003; 289: 2801-9.


34% mortality rate from SARS in critically ill patients at 28 days in Toronto.
Fowler RA, Lapinsky SE, Hallett D, et al. JAMA. 2003; 290: 367-73.


37% mortality rate from SARS in critically ill patients at 28 days in Singapore.
Lew TW, Kwek TK, Tai D, et al. JAMA. 2003; 290: 374-80.


Quality improvement
A nurse-facilitator intervention improved the use of β-blockers in outpatients with stable congestive heart failure.
Ansari M, Shlipak MG, Heidenreich PA, et al. Circulation. 2003; 107: 2799-804.


Noninvasive ventilation was cost-effective for reducing in-hospital mortality in COPD.
Plant PK, Owen JL, Parrott S, Eliott MW. BMJ. 2003; 326: 956-9.


Clinical prediction guide
Review: Absence of somatosensory-evoked potentials after onset of coma has a high specificity for predicting nonawakening.
Robinson LR, Micklesen PJ, Tirschwell DL, Lew HL. Crit Care Med. 2003; 31: 960-7.


A prediction rule identified patients with atrial fibrillation at low risk for stroke while taking aspirin.
van Walraven C, Hart RG, Wells GA, et al. Arch Intern Med. 2003; 163: 936-43.