ACP Journal Club

(更新日 2007年12月19日)
 ACP Journal Clubの紹介(タイトル和訳)
  July/August 2007 volume 147 Number 1
 (福岡大学医学部 心臓・血管内科学 高宮陽介/木谷嘉博/三戸隆裕/今泉聡/野田慶太/朔啓二郎*)
*Publication Committee副委員長

Review: Lifestyle or pharmacologic interventions prevent or delay type 2 diabetes in impaired glucose tolerance.
Gilles CL, Abrams KR, Lambert PC, et al. BMJ. 2007;334:299.


Intensive insulin therapy during cardiac surgery did not reduce mortality or morbidity but increased risk for stroke.
Gandhi GY, Nuttall GA, Abel MD, et al. J Ann Intern Med. 2007;146:233-43.


An intensive smoking cessation intervention reduced mortality in high-risk smokers with cardiovascular disease.
Mohiuddin SM, Mooss AN, Hunter CB, et al. Chest. 2007;131:446-52.


Review: Antioxidant supplements for primary and secondary prevention do not decrease mortality.
Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. JAMA. 2007;297:842-57.


An exercise program led to a slower decline in activities of daily living in nursing-home patients with Alzheimer disease.
Rolland Y, Pillard F, Klapouszczak A, et al. J Am Geriatr Soc. 2007;55:158-65.


Review: Periodic health examination increases delivery of some clinical preventive services and reduces patient worry.
Boulware LE, Marinopoulos S, Phillips KA, et al. Ann Intern Med. 2007;146:289-300.


Review: Flight times > 8 hours and the presence of risk factors for VTE increase travel-related VTE.
Philbrick JT, Shumate R, Siadaty MS, Becker DM. J Gen Intern Med. 2007;22:107-14.


Once-daily oral controller therapy with low-dose theophylline or montelukast was not effective in poorly controlled asthma.
The American Lung Association Asthma Clinical Research Centers. Am J Respir Crit Care Med. 2007;175:235-42.


Review: Drugs for mild-to-moderate hypertension in pregnancy reduce risk for severe hypertension but not preeclampsia.
Abalos E, Duley L, Steyn D, Henderson-Smart DJ. Cochrane Database Syst Rev. 2007;(1):CD002252.


Stress echocardiography safely classified more patients as low risk for serious CAD than exercise electrocardiography.
Jeetley P, Burden L, Stoykova B, Senior R. Eur Heart J. 2007; 28:240-11.


Review: Rescue percutaneus coronary intervention but not repeated fibrinolysis is effective for failed fibrinolysis in STEMI.
Wijeysunddera HC, Vijayaraghavan R, Nallamothu BK, et al.


Percutaneus coronary intervention plus optimal medical therapy was not more effective than medical therapy alone in stable CAD.
Boden WE, O’Rourke RA, Teo KK, et al. N Engl J Med. 2007;356: 1503-16.


Review: Drug-eluting stents are more effective than bare-metal stents for reducing acute MI at 6 to 12 months after implantation.
Moreno R, Fernandez C, Calvo L, et al. Am J Cardiol. 2007;99: 621-5.


Review: Sirolimus-eluting stents do not differ from bare-metal stents for long-term survival in CAD.
Kastrati A, Mehilli J, Pache J, et al. N Engl J Med. 2007;356:1030-9.


Review: Evidence from observational studies, but not randomized trials, suggests that long-term aspirin prevents colorectal cancer.
Dube C, Rostom A, Lewin G, et al. a systematic review prepared for the U.S. Preventive Services Task Force. Ann Intern Med. 2007;146:365-75.


Review: NSAIDs and COX-2 inhibitors may prevent colorectal cancer but increase gastrointestinal and cardiovascular harm.
Rostom A, Dube C, Lewin G, et al. Ann Intern Med. 2007;146:376-89.


Review: Anticoagulants increase intracerebral bleeding and do not reduce death or disability in acute cardioembolic stroke.
Paciaroni M, Agnelli G, Micheli S, Caso V. a meta-analysis of randomized controlled trials. Stroke. 2007;38:423-30.

Early infusion of high-dose omeprazole before endoscopy reduced the need for endoscopic therapy.
Lau JY, Leung WK, Wu JC,et al. N Engl J Med. 2007;56:1631-40.

Review: Neoadjuvant chemoradiotherapy and chemotherapy improve survival in operable esophageal cancer.
Gebski V, Burmeister B, Smithers BM et al. Lancet oncol. 2007;8:226-34.



Magnetic resonance imaging is an accurate test for diagnosing foot osteomyelitis.
Kapoor A, Page S, LaValley M, Gale DR, Felson Dt. Arch Intern Med. 2007;167:125-32.


Review: Commercial interferon-γ release have high specificity but suboptimal sensitivity for detecting latent TB.
Menzies D, Pai M, Comstock G. Ann Intern Med. 2007;146:340-54.



Absolute risk for subsequent fracture was similar in women and men.
Center JR, Bliuc D, Nguyen TV, Eisman JA. JAMA. 2007;297:387-94.



Conventional antipsychotic drugs increased risk for death more than did atypical antipsychotic drugs in elderly patients.
Schneeweiss S, Setoguchi S, et al. CMAJ. 2007;176:627-32.



Aspirin was cost-effective for primary prevention of cardiovascular events in older women at moderate risk.
Pignone M, Earnshaw S, Pletcher MJ, Tice JA. Arch Intern Med. 2007;167:290-5.


Clinical prediction guide

A clinical risk score identified high-risk patients with chest pain but no ST-segment deviation and normal troponin levels.
Sanchis J, Bodf V, et al. Am J Cardiol. 2007;99:797-801.