(更新日 2008年6月2日)

ACP Journal Clubの紹介(タイトル和訳)

March/April 2008 Volume 148 Number 2
(福岡大学医学部 心臓・血管内科学 小吉 里枝/斎藤 尚子/杉原 充/野田慶太/朔啓二郎*)
*Publication Committee副委員長

Early treatment with prednisolone, but not acyclovir, promoted complete recovery of facial-nerve function in Bell palsy.
Sullivan FM, Swan IR, Donnan PT, et al.N Engl J Med. 2007;357:1598-607.
Review: Vitamin D supplementation decreases all-cause mortality in adults and older individuals.
Autier P, Grandini S. Arch Intern Med. 2007;167:1730-7.
Primary prevention with pravastatin for 5 years continued to prevent coronary events in the following 10 years.
Ford I, Murray H, Packard CJ, et al. N Engl J Med. 2007;357:1447-86.
Heparin prophylaxis did not increase mortality and was beneficial in adults with sepsis receiving drotrecogin alfa.
Levi M, Levy M, Williams MD, et al. Am J Respir Crit Med. 2007;176:483-90.
drotrecogin alfaによる治療を受けている重症敗血症の成人においてヘパリンによる血栓予防は死亡率を増加させず,他の臨床成績に関しても安全であった.
Donepezil was no better than placebo for agitation in patients with Alzheimer disease.
Howard RJ, Juszczak E, Ballard CG, et al. N Engl J Med. 2007;357:1382-92.
Addition of clopidogrel to aspirin may have increased risk for cardiovasucular death in a primary prevention population.
Wang TH, Bhatt DL, Fox KA, et al. Eur Heart J. 2007;28:2200-7.
Review: Angiotensin II receptor blocker plus angiotensin-converting enzyme inhibitor increases risk for adverse effects.
Phillips CO, Kashani A, Ko DK, Francis G, Krumholz HM. Arch Intern Med. 2007;167:1930-6.
Aerobic plus resistance training was more effective than either alone for reducing HbA1c levels in type2 diabetes.
Sigal RJ, Kenny GP, Boule NG, et al. Ann Intern Med. 2007;147:357-69.
Review: Long-acting insulin analogues do not improve glycemic control but do reduce nocturnal hypoglycemia in diabetes.
Tran K, Banerjee S, Li H, et al. Technology report #92. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH);2007.
Review: β-blockers for hypertension increase risk for new-onset diabetes compared with nondiuretic antihypertensive agents.
Bangalore S, Parker S, Grossman E, Messerli FH. Am J Cardiol. 2007;100:1254-62.
Review: Thiazolidinediones increase congestive heart failure but not cardiovascular deaths in prediabetes or type2 diabetes.
Lago RM, Singh PP, Nesto RW. Lancet. 2007;370:1129-36.
Intravenous zoledronic acid reduced new clinical fractures and deaths in patients who had recent surgery for hip fracture.
Lyles KW, colon-Emeric CS, Magaziner JS, et al. N Engl J Med. 2007;357:1799-809.
股関節骨折の術後早期の患者においてzoledronic acidの静脈内注射は新たな骨折や死亡を減少させた.
Review: Calcium supplementation, with or without vitamin D, prevents osteoporotic fractures in people50 years of age.
Tang BM, Eslick GD, Nowson C, Bensonoussan A. Lancet. 2007;370:657-66.
メタ解析によるとビタミンDの有無にかかわらずカルシウムの補給はプラセボに比較して骨粗鬆症による骨折の危険性を減少させ,大腿骨骨頭(平均骨密度差0.54%,CI 0.35-0.75,24試験,n=44990)と脊椎(平均骨密度差1.19%,CI 0.76-1.61,24試験,n=3913)の骨量減少を低下させた.
Intraarticular hylan was no better than hyaluronic acids for osteoarthritis of the knee.
Juni P, Reichenbach S, Trelle S, et al. Arthritis Rheum. 2007;56:3610-9.
Prophylactic hemodialysis after coronary angiography improved renal outcomes in patients with advanced renal failure.
Lee PT, Chou KJ, Liu CP, et al. J Am Coll Cardiol. 2007;50:1015-20.
Review: PCI has lower risk for procedural stroke but higher risks for angina and repeated revascularization than CABG.
Bravata DM, Gienger AL, McDonald KM, et al. Ann Intern Med. 2007;147:703-16.
Pharmacogenetic-guided and standard dosing did not differ for out-of-range INRs in patients initiating warfarin therapy.
Anderson JL, Horne BD, Stevens SM, et al. Circulation. 2007;116:2563-70.
Self-management of oral anticoagulation with low- or conventional- intensity INR did not differ for thromboembolism prevention.
Koertke H, Zittermann A, Tenderich G, et al. Eur Heart J. 2007;28:2479-84.
Review: Self-testing or self-management of anticoagulation is better than clinic monitoring for thromboembolism and mortality.
Connock M, Stevens C, Fry-Smith A, et al. Health Technol Assess. 2007;11:iii-iv, ix-66.
Review: Long-acting inhaled therapies and pulmonary rehabilitation are effective in stable COPD.
Wilt TJ, Niewoehner D, Macdonald R, Kane RL. Ann Intern Med. 2007;147:639-53.
Review: Corticosteroids plus long-acting β-angonists reduce exacerbations more than long-acting β-agonists alone in COPD.
Nannini L, Cates C, Lasserson T, Poole P. Cochrase Database Syst Rev. 2007;(4):CD006829.
Review: Orlistat, sibutramine, and rimonabant reduce weight in overweight and obese persons.
Rucker D, Padwal R, Li SK, Curioni C, Lau DC. BMJ. 2007;335:1194-9.
Computed tomographic angiography had high sensitivity for coronary artery disease in patients at intermediate risk.
Hausleiter J, Meyer T, Hadamitzky M, et al. Eur Heart J. 2007;28:3034-41.
A personalized mailed brochure was cost-effective for promoting colonoscopy in asymptomatic patient referred for screening.
Shankaran V, McKoy JM, Dandade N, et al. J Clin Oncol. 2007;25:5248-53.
Second-generation antipsychotics did not improve outcomes and increased cost for patients with Alzhemer disease and psychosis.
Rosenheck RA, Leslie DL, Sindelar JL, et al. Arch Gen Psychiatry. 2007;64:1259-68.